NOA: a cytoscape plugin for network ontology analysis

نویسندگان

  • Chao Zhang
  • Jiguang Wang
  • Kristina Hanspers
  • Dong Xu
  • Luonan Chen
  • Alexander R. Pico
چکیده

SUMMARY The Network Ontology Analysis (NOA) plugin for Cytoscape implements the NOA algorithm for network-based enrichment analysis, which extends Gene Ontology annotations to network links, or edges. The plugin facilitates the annotation and analysis of one or more networks in Cytoscape according to user-defined parameters. In addition to tables, the NOA plugin also presents results in the form of heatmaps and overview networks in Cytoscape, which can be exported for publication figures. AVAILABILITY The NOA plugin is an open source, Java program for Cytoscape version 2.8 available via the Cytoscape App Store (http://apps.cytoscape.org/apps/noa) and plugin manager. A detailed user manual is available at http://nrnb.org/tools/noa. .ucsf.edu

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Mosaic: making biological sense of complex networks

UNLABELLED We present a Cytoscape plugin called Mosaic to support interactive network annotation, partitioning, layout and coloring based on gene ontology or other relevant annotations. AVAILABILITY Mosaic is distributed for free under the Apache v2.0 open source license and can be downloaded via the Cytoscape plugin manager. A detailed user manual is available on the Mosaic web site (http://...

متن کامل

BiNoM: a Cytoscape plugin for using and analyzing biological networks

BiNoM (BIological NetwOrk Manager) is a Cytoscape plugin, developed to facilitate the manipulation of biological networks represented in standard systems biology formats and to carry out studies on the network structure. BiNoM provides the user with a complete interface for the analysis of biological networks in Cytoscape environment. BiNoM plugin with documentation, API and source code is avai...

متن کامل

PiNGO: a Cytoscape plugin to find candidate genes in biological networks

UNLABELLED PiNGO is a tool to screen biological networks for candidate genes, i.e. genes predicted to be involved in a biological process of interest. The user can narrow the search to genes with particular known functions or exclude genes belonging to particular functional classes. PiNGO provides support for a wide range of organisms and Gene Ontology classification schemes, and it can easily ...

متن کامل

Ontology- and graph-based similarity assessment in biological networks

SUMMARY A standard systems-based approach to biomarker and drug target discovery consists of placing putative biomarkers in the context of a network of biological interactions, followed by different 'guilt-by-association' analyses. The latter is typically done based on network structural features. Here, an alternative analysis approach in which the networks are analyzed on a 'semantic similarit...

متن کامل

CytoCluster: A Cytoscape Plugin for Cluster Analysis and Visualization of Biological Networks

Nowadays, cluster analysis of biological networks has become one of the most important approaches to identifying functional modules as well as predicting protein complexes and network biomarkers. Furthermore, the visualization of clustering results is crucial to display the structure of biological networks. Here we present CytoCluster, a cytoscape plugin integrating six clustering algorithms, H...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 29  شماره 

صفحات  -

تاریخ انتشار 2013